HLA haplotypes, polysomnography, and pedigrees in a case series of patients with narcolepsy.

@article{Hayduk1997HLAHP,
  title={HLA haplotypes, polysomnography, and pedigrees in a case series of patients with narcolepsy.},
  author={Roza Hayduk and Pamela Flodman and M. Anne Spence and Milton K. Erman and Merrill M. Mitler},
  journal={Sleep},
  year={1997},
  volume={20 10},
  pages={850-7}
}
An ongoing study of the genetics of narcolepsy ascertains families through a case series of narcoleptic probands using diagnostic criteria consisting of 1) clinical history of excessive somnolence, 2) a mean sleep latency on the multiple sleep latency test (MSLT) of less than 7.9 minutes, 3) the rapid eye movement (REM) sleep-related symptom of cataplexy, 4) nocturnal polysomnography ruling out sleep apnea syndrome, and 5) two or more transitions to REM sleep on the MSLT. All probands and first… CONTINUE READING