HLA gene and haplotype frequencies in Russians, Bashkirs and Tatars, living in the Chelyabinsk Region (Russian South Urals)

  title={HLA gene and haplotype frequencies in Russians, Bashkirs and Tatars, living in the Chelyabinsk Region (Russian South Urals)},
  author={Tatiana A Suslova and A. L. Burmistrova and M S Chernova and E B Khromova and Ekaterina Lupar and S. V. Timofeeva and I. V. Devald and Mikhail N. Vavilov and C. Darke},
  journal={International Journal of Immunogenetics},
We have characterized the HLA‐A, ‐B, ‐DRB1, ‐DQA1 and ‐DQB1 profiles of three major ethnic groups living in Chelyabinsk Region of Russian South Urals, viz., Russians (n = 207), Bashkirs (n = 146) and Tatars (n = 135). First field level typing was performed by PCR using sequence‐specific primers. Estimates included carriage and gene frequencies, linkage disequilibrium and its significance and related values. Population comparisons were made between the allele family frequencies of the three… Expand
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