HLA class II transgenic mice develop a safe and long lasting immune response against StreptInCor, an anti-group A streptococcus vaccine candidate.

Abstract

Streptococcus pyogenes infections remain a health problem in several countries because of post-streptococcal sequelae, such as rheumatic fever and rheumatic heart disease. We developed a vaccine epitope (StreptInCor) composed of 55 amino acid residues of the C-terminal portion of the M protein that encompasses both T and B cell protective epitopes. Recently… (More)
DOI: 10.1016/j.vaccine.2011.08.113

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Cite this paper

@article{Guerino2011HLACI, title={HLA class II transgenic mice develop a safe and long lasting immune response against StreptInCor, an anti-group A streptococcus vaccine candidate.}, author={Milton T Guerino and Edilberto Post{\'o}l and L{\'e}a Maria Macruz Ferreira Demarchi and Carlo de Oliveira Martins and Luiz R Mundel and Jorge Agle Kalil and Luiza Guilherme}, journal={Vaccine}, year={2011}, volume={29 46}, pages={8250-6} }