HLA class II molecules transduce accessory signals affecting the CD3 but not the interleukin-2 activation pathway in T blasts.

@article{Rosa1993HLACI,
  title={HLA class II molecules transduce accessory signals affecting the CD3 but not the interleukin-2 activation pathway in T blasts.},
  author={Francesca Di Rosa and Ugo D'Oro and Giuseppina Ruggiero and Luigi Racioppi and Andrea Acquaviva and Soldano Ferrone and Silvia Fontana and Serafino Zappacosta},
  journal={Human immunology},
  year={1993},
  volume={38 4},
  pages={251-60}
}
MHC class II molecules play a central role in the control of the immune response, but their biologic function and mechanism of action on the surface of activated human T lymphocytes are not entirely understood. In our study, the functional role of HLA class II molecules in T-blast proliferation was investigated by analyzing in parallel the IL-2- and CD3… CONTINUE READING