HLA class II genotypes associated with chronic hepatitis C virus infection and response to alpha-interferon treatment in Poland.

@article{WawrzynowiczSyczewska2000HLACI,
  title={HLA class II genotypes associated with chronic hepatitis C virus infection and response to alpha-interferon treatment in Poland.},
  author={Marta Wawrzynowicz-Syczewska and James A Underhill and Michael A Clare and Anna Boroń-Kaczmarska and I G Mcfarlane and Peter T. Donaldson},
  journal={Liver},
  year={2000},
  volume={20 3},
  pages={234-9}
}
AIMS/BACKGROUND Recent evidence suggests that spontaneous clearance of hepatitis C virus (HCV) may be associated with the HLA DQB1*0301 allele but there is still some debate over the role of other alleles and HLA haplotypes in HCV infection. As this may best be resolved by studying genetically different populations, we have investigated HLA class II-encoded susceptibility and resistance to HCV infection in a relatively sedentary population of patients from northwestern Poland. METHODS The… CONTINUE READING

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