HLA class II antibodies in transfusion-related acute lung injury.

  title={HLA class II antibodies in transfusion-related acute lung injury.},
  author={Patricia M. Kopko and Mark A. Popovsky and Malcolm R. Mackenzie and Teresa G Paglieroni and Kathryn N Muto and Paul V. Holland},
  volume={41 10},
BACKGROUND Transfusion-related acute lung injury (TRALI) is a serious, sometimes fatal, complication of transfusion. Granulocyte and HLA class I antibodies present in blood donors have been associated with TRALI. HLA class II antibodies have recently been described in a few cases of TRALI. STUDY DESIGN AND METHODS Donors involved in TRALI reactions reported to a blood center over an 18-month period were tested for HLA class I and II antibodies as well as granulocyte antibodies, if HLA… CONTINUE READING

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[Pulmonary complications of transfusion (TACO-TRALI)].

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine • 2009
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