HLA-class I markers and multiple sclerosis susceptibility in the Italian population

@article{Bergamaschi2010HLAclassIM,
  title={HLA-class I markers and multiple sclerosis susceptibility in the Italian population},
  author={Laura Ben{\'i}cio Cruz Bergamaschi and M A Leone and Maria Edvige Fasano and Franca Rosa Guerini and Daniela Ferrante and Elisabetta Bolognesi and Nadia Barizzone and Lucia Corrado and Paola Naldi and Cristina Agliardi and Ennia Dametto and Marco Salvetti and Andrea Visconti and Daniela Galimberti and Elio Scarpini and Marco Vercellino and Roberto Bergamaschi and Francesco Monaco and Domenico Caputo and Patricia Momigliano-Richiardi and Sandra D'alfonso},
  journal={Genes and Immunity},
  year={2010},
  volume={11},
  pages={173 - 180}
}
Previous studies reported an association with multiple sclerosis (MS) of distinct HLA-class I markers, namely HLA-A*02, HLA-Cw*05 and MOG-142L. In this work, we tested the association with MS of A*02 and Cw*05 in 1273 Italian MS patients and 1075 matched controls, which were previously analyzed for MOG-142, and explored the relationship among these three markers in modulating MS risk. HLA-A*02 conferred a statistically robust MS protection (odds ratio, OR=0.61; 95% confidence intervals, CI=0.51… CONTINUE READING
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