HLA class 2 genes in Singaporean Chinese rheumatoid arthritis.

@article{Chan1994HLAC2,
  title={HLA class 2 genes in Singaporean Chinese rheumatoid arthritis.},
  author={Samuel H. P. Chan and Y. N. Lin and G. B. Wee and Wook Hee Koh and Mee Leng Boey},
  journal={British journal of rheumatology},
  year={1994},
  volume={33 8},
  pages={
          713-7
        }
}
This study analysed HLA class 1 and 2 allele associations in Singaporean Chinese patients with RA. Seventy patients (ARA definite or classical) and 80 controls were typed for HLA class 1 alleles by serology and class 2 alleles by serology and the PCR/SSO method. RA patients had higher frequencies of DRB1*0405 (40 vs 12.5%; corrected probability value (PC) < 0.02, relative risk (RR) = 4.7, 95% confidence limit (CL) 2.1-10.6), DRB1*1001 (14.3 vs 1.3%; PC = 0.06, RR = 13.2, 95% CL 1.6-105.7), DQB1… CONTINUE READING

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Meta-analysis of the Association between HLA-DRB1 Allele and Rheumatoid Arthritis Susceptibility in Asian Populations

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