HLA antigens and islet cell antibodies in gestational diabetes.

  title={HLA antigens and islet cell antibodies in gestational diabetes.},
  author={Pablo Rubinstein and Mark J Walker and J Krassner and C. Carrier and Clyde T Carpenter and Michael J. Dobersen and Abner Louis Notkins and E M Mark and C Nechemias and Richard Hausknecht and Fredda V Ginsberg-Fellner},
  journal={Human immunology},
  volume={3 3},
The HLA antigens of 136 patients with gestational diabetes are compared with control populations. No significant variations are observed in their frequencies, particularly for those antigens associated with Type 1 diabetes mellitus. Islet cell antibodies have also been studied in the serum of 52 of these patients and 20 of them were positive, whereas only one of 37 pregnant nondiabetic women had such antibodies (chi 2 = 15.2). A very high association between ICA and DR3 and DR4 was encountered… CONTINUE READING