HLA antigen expression at the single cell level on a K562 × B cell hybrid: An analysis with monoclonal antibodies using bacterial binding assays

@article{Ziegler1982HLAAE,
  title={HLA antigen expression at the single cell level on a K562 × B cell hybrid: An analysis with monoclonal antibodies using bacterial binding assays},
  author={Andreas Ziegler and Barbara Uchańska-Ziegler and Jesper Zeuthen and Peter Wernet},
  journal={Somatic Cell Genetics},
  year={1982},
  volume={8},
  pages={775-789}
}
The influence of different genetic environments on the expression of HLA complex-controlled antigens has been investigated using cell lines with various defects in the synthesis of these molecules and a somatic cell hybrid derived from them. A very sensitive bacterial binding assay allowing simultaneous evaluation of the morphology of a given cell and the quantity of a surface molecule has been developed for these studies. The fetal erythroid cell line K562, the Burkitt's lymphoma-derived cell… CONTINUE READING

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