HLA and killer cell immunoglobulin-like receptors influence the natural course of CMV infection.

@article{Bona2014HLAAK,
  title={HLA and killer cell immunoglobulin-like receptors influence the natural course of CMV infection.},
  author={Danilo Di Bona and Valeria Scafidi and Antonella Plaia and Claudia Colomba and Domenico Nuzzo and Cecilia Occhino and Antonino Tuttolomondo and Giovanni M. Giammanco and Simona De Grazia and Giuseppe Montalto and Giovanni Duro and Marco Cippitelli and Calogero Caruso},
  journal={The Journal of infectious diseases},
  year={2014},
  volume={210 7},
  pages={1083-9}
}
BACKGROUND Natural killer (NK) cells provide a major defense against cytomegalovirus (CMV) infection through the interaction of their surface receptors, including the activating and inhibitory killer immunoglobulin-like receptors (KIRs), and human leukocyte antigens (HLA) class I molecules. This study assessed whether the KIR and HLA repertoire may influence the risk of developing symptomatic or asymptomatic disease after primary CMV infection in the immunocompetent host. METHODS Sixty… CONTINUE READING
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