HLA and disease

@article{Ghodke2005HLAAD,
  title={HLA and disease},
  author={Yogita Ghodke and Kalpana Joshi and Arvind Chopra and Bhushan Patwardhan},
  journal={European Journal of Epidemiology},
  year={2005},
  volume={20},
  pages={475-488}
}
Association of HLA and diseases is well known. Several population studies are available suggesting evidence of association of HLAs in more than 40 diseases. HLA found across various populations vary widely. Some of the reasons attributed for such variation are occurrence of social stratification based on geography, language and religion, consequences of founder effect, racial admixture or selection pressure due to environmental factors. Hence certain HLA alleles that are predominantly… CONTINUE READING