HLA alleles modulate EBV viral load in multiple sclerosis

@inproceedings{Agostini2018HLAAM,
  title={HLA alleles modulate EBV viral load in multiple sclerosis},
  author={Simone Agostini and Roberta A. Mancuso and Franca Rosa Guerini and Sandra D'alfonso and Cristina Agliardi and Ambra Hernis and Milena Zanzottera and Nadia Barizzone and M Leone and Dennis L. Caputo and Marco Rovaris and Mario Clerici},
  booktitle={Journal of Translational Medicine},
  year={2018}
}
BackgroundThe etiopathology of multiple sclerosis (MS) is believed to include genetic and environmental factors. Human leukocyte antigen (HLA) alleles, in particular,  are associated with disease susceptibility, whereas Epstein Barr Virus (EBV) infection has long been suspected to play a role in disease pathogenesis. The aim of the present study is to evaluate correlations between HLA alleles and EBV infection in MS.MethodsHLA alleles, EBV viral load (VL) and serum anti-EBV antibody titers were… CONTINUE READING
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