HLA-G polymorphisms and soluble HLA-G protein levels in women with recurrent pregnancy loss from Basrah province in Iraq.

@article{Jassem2012HLAGPA,
  title={HLA-G polymorphisms and soluble HLA-G protein levels in women with recurrent pregnancy loss from Basrah province in Iraq.},
  author={Raghed M. Jassem and Wafaa Sadoon Shani and Dagan A Loisel and Maysoon Sharief and Christine Billstrand and Carole Ober},
  journal={Human immunology},
  year={2012},
  volume={73 8},
  pages={811-7}
}
HLA-G is a nonclassical, class I major histocompatibility complex (MHC) gene that exhibits immunomodulatory properties and likely plays a role in the maintenance of successful pregnancy. In this study, we investigated the role of HLA-G polymorphisms on risk for recurrent pregnancy loss (RPL) and on circulating levels of soluble (s)HLA-G in Iraqi women. DNA and plasma were obtained from blood samples collected at 9-12 weeks gestation from 50 women with RPL and 50 healthy pregnant women in Basrah… CONTINUE READING

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