HLA-G genotype is associated with fetoplacental growth.

  title={HLA-G genotype is associated with fetoplacental growth.},
  author={Thomas Vauvert F Hviid},
  journal={Human immunology},
  volume={65 6},
The human leukocyte antigen (HLA)-G is expressed by extravillous cytotrophoblast cells in the feto-maternal contact zone. Polymorphisms have been described in the HLA-G gene and have been linked with differences in HLA-G mRNA alternative splicing patterns and protein expression. Differences in the isoform profile or the degree of HLA-G expression may influence cytokine production and, thereby, placental and fetal growth. Associations between a 14 bp deletion polymorphism in the 3'UTR part of… CONTINUE READING
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