HLA-G expression is up-regulated by progesterone in mesenchymal stem cells.

@article{IvanovaTodorova2009HLAGEI,
  title={HLA-G expression is up-regulated by progesterone in mesenchymal stem cells.},
  author={Ekaterina I Ivanova-Todorova and Milena Mourdjeva and Dobroslav Stanimirov Kyurkchiev and Ivan Bochev and Elena Stoyanova and Rumen D. Dimitrov and Tanya Timeva and Maria Yunakova and Dimitar Bukarev and Atanas Shterev and Petar Tivchev and Stanimir Dobrev Kyurkchiev},
  journal={American journal of reproductive immunology},
  year={2009},
  volume={62 1},
  pages={25-33}
}
PROBLEM Maternal immune response to fetal tissues is modified in such way that it favors the development of pregnancy. Human leukocyte antigen (HLA)-G, progesterone and mesenchymal stem cells (MSCs) have been identified as potent immunomodulatory agents in different experimental systems and the interactions between these three factors are studies in this paper. METHOD OF STUDY Human MSCs are isolated from human adipose tissue, bone marrow and decidua are cultured in the presence of… CONTINUE READING