HLA-G and its role in implantation (review)

  title={HLA-G and its role in implantation (review)},
  author={R. Roussev and C. Coulam},
  journal={Journal of Assisted Reproduction and Genetics},
  • R. Roussev, C. Coulam
  • Published 2007
  • Medicine, Biology
  • Journal of Assisted Reproduction and Genetics
  • BackgroundHuman leukocyte antigen G (HLA-G) is thought to play a key role in implantation by modulating cytokine secretion to control trophopblastic cell invasion and to maintain a local immunotolerance.Method of studyThe literature is reviewed to provide a description of the genetic background, properties of the protein, and the function of HLA-G. Data are presented on potential clinical applications of HLA-G including the use of evaluation of HLA-G gene polymorphisms in the diagnosis of… CONTINUE READING
    HLA-G as a Tolerogenic Molecule in Transplantation and Pregnancy
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