HLA-G and its role in implantation (review)

  title={HLA-G and its role in implantation (review)},
  author={Roumen G. Roussev and Carolyn B Coulam},
  journal={Journal of Assisted Reproduction and Genetics},
Human leukocyte antigen G (HLA-G) is thought to play a key role in implantation by modulating cytokine secretion to control trophopblastic cell invasion and to maintain a local immunotolerance. The literature is reviewed to provide a description of the genetic background, properties of the protein, and the function of HLA-G. Data are presented on potential clinical applications of HLA-G including the use of evaluation of HLA-G gene polymorphisms in the diagnosis of patients experiencing… CONTINUE READING
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HLA-G upregulates ILT2, ILT3, ILT4, and KIR2DL4 in antigen-presenting cells, NK cells, and T cells

  • J LeMaoult, K Zafaranloo, C Le Danff, ED. Carosella
  • FASEB J 2005;19:662–4
  • 2005
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Report of the wet workshop for quantification of soluble HLAG in Essen , 2004

  • V Rebmann, J Lamaoult, N Rouas-Freiss, ED Carosella, H Grosse-Wilde
  • Hum Immunol
  • 2005

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