HLA-G 14-bp insertion/deletion polymorphism in kidney transplant patients with metabolic complications.

@article{Piancatelli2009HLAG1I,
  title={HLA-G 14-bp insertion/deletion polymorphism in kidney transplant patients with metabolic complications.},
  author={Daniela Piancatelli and Daniela Maccarone and Gabriella Liberatore and Ilaria Parzanese and Katia Clemente and R. Azzarone and Francesco Pisani and Antonio Famulari and Franco Papola},
  journal={Transplantation proceedings},
  year={2009},
  volume={41 4},
  pages={1187-8}
}
HLA-G, a nonclassical HLA molecule with limited polymorphism has immunomodulating/tolerogenic properties. The most common polymorphism of HLA-G is a deletion/insertion of 14 bp, located at the 3'UTR region of the gene (exon 8). This polymorphism is associated with modifications of mRNA stability that can lead to variations of membrane versus soluble HLA-G… CONTINUE READING