HLA DRB1*15-DPB1*05 haplotype: a susceptible gene marker for isocyanate-induced occupational asthma?

@article{Kim2006HLADH,
  title={HLA DRB1*15-DPB1*05 haplotype: a susceptible gene marker for isocyanate-induced occupational asthma?},
  author={Seung-Hyun Kim and H B Oh and K M Lee and E-S Shin and Chan Wha Kim and C. S. Hong and D-H Nahm and Hyungbin Park},
  journal={Allergy},
  year={2006},
  volume={61 7},
  pages={891-4}
}
BACKGROUND There has been no study for evaluating the associations of human leukocyte antigen (HLA) class I and II alleles with toluene diisocyanate (TDI)-induced asthma in an Asian population. OBJECTIVE The aim of this study was to investigate a susceptible or protective marker of HLA class I and II alleles in TDI-induced asthma. METHODS Fifty-five patients with TDI-induced asthma patients (group I) showing positive responses on TDI bronchoprovocation test, 47 asymptomatic exposed subjects… CONTINUE READING

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