HLA-DRB1*0404 is strongly associated with high titers of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis.

Abstract

OBJECTIVE To test whether the presence of RA associated HLA-DRB1*0101, HLA-DRB1*0401 and HLA-DRB1*0404 alleles individually influences anti-cyclic citrullinated peptide antibodies (anti-CCP) production. METHODS The frequency of anti-CCP antibodies was calculated in the sera of 260 RA patients expressing either two (double dose genotypes SE+/SE+), one… (More)

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@article{Charpin2008HLADRB10404IS, title={HLA-DRB1*0404 is strongly associated with high titers of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis.}, author={C. Charpin and Nathalie Balandraud and Sandrine Guis and Candice Roudier and Enc Toussirot and Justyna Rak and N. Lambert and M. Mart{\'i}n and Denis Vincent Reviron and Jean Roudier and I. E. Auger}, journal={Clinical and experimental rheumatology}, year={2008}, volume={26 4}, pages={627-31} }