• Biology, Medicine
  • Published in Cancer research 1997

HLA-DRB1*0101 and *0405 as protective alleles in Japanese patients with renal cell carcinoma.

@article{Ozdemir1997HLADRB10101A,
  title={HLA-DRB1*0101 and *0405 as protective alleles in Japanese patients with renal cell carcinoma.},
  author={Emircan Ozdemir and Yoshiyuki Kakehi and Eijiro Nakamura and Hidefumi Kinoshita and T Terachi and Yusaku Okada and Osamu Yoshida},
  journal={Cancer research},
  year={1997},
  volume={57 4},
  pages={
          742-6
        }
}
A variety of malignancies have been linked to major histocompatibility complex genes, including the DRB1 alleles. The association of certain DRB1 antigens with renal cell carcinoma (RCC) has been both claimed and disclaimed. To determine whether HLA-DRB1 genotypes are associated with RCC, we used the modified PCR-RFLP method for the high-resolution HLA-DRB1 genotyping of 96 Japanese RCC patients. There were no significantly frequent HLA-DRB1 alleles, whereas the DRB1*0101 and *0405 alleles had… CONTINUE READING

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Genetic polymorphisms of the interleukin-4 receptor alpha gene are associated with an increasing risk and a poor prognosis of sporadic renal cell carcinoma in a Japanese population.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 2002
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