HLA-DRB1, DQA1 and DQB1 alleles and haplotypes frequencies in Iranian healthy adult responders and non-responders to recombinant hepatitis B vaccine.

@article{Amirzargar2008HLADRB1DA,
  title={HLA-DRB1, DQA1 and DQB1 alleles and haplotypes frequencies in Iranian healthy adult responders and non-responders to recombinant hepatitis B vaccine.},
  author={Ali Akbar Amirzargar and Nilufar Mohseni and Mohammad Ali Shokrgozar and Zohreh Arjang and Nahid Ahmadi and Manijeh Yousefi Behzadi and Amir Amanzadeh and F Askari Seyed Shokri},
  journal={Iranian journal of immunology : IJI},
  year={2008},
  volume={5 2},
  pages={
          92-9
        }
}
BACKGROUND Different studies have demonstrated that a small proportion of healthy individuals receiving the hepatitis B (HB) vaccine do not produce protective levels of anti-HB antibody, a phenomenon which could be linked to certain human leukocyte antigen (HLA) class-II alleles or haplotypes. OBJECTIVES The present study was undertaken to determine the frequency of HLA class-II alleles in Iranian healthy adult responders and non-responders to HB vaccine. METHODS Twelve non-responders (anti… CONTINUE READING

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