HLA-DR2 and narcolepsy.


A positive association between HLA-DR2, DQw1, and narcolepsy was documented in 23 French caucasoid narcoleptic patients, 18 who were heterozygous for DR2 and 5 who were possibly homozygous. An autoimmune mechanism of narcolepsy is proposed with three successive stages, as well as relevant methodology for further investigation. A dominant mode of inheritance… (More)


Cite this paper

@article{Billiard1986HLADR2AN, title={HLA-DR2 and narcolepsy.}, author={Michel M. Billiard and J. Seignalet and Alain Besset and J C Cadilhac}, journal={Sleep}, year={1986}, volume={9 1 Pt 2}, pages={149-52} }