HLA-DR beta genes vary in number between different DR specificities, whereas the number of DQ beta genes is constant.

@article{Bhme1985HLADRBG,
  title={HLA-DR beta genes vary in number between different DR specificities, whereas the number of DQ beta genes is constant.},
  author={Jan B{\"o}hme and Mikael Svante Andersson and G{\"o}ran Andersson and Emely M{\"o}ller and Per A. Peterson and Lars Rask},
  journal={Journal of immunology},
  year={1985},
  volume={135 3},
  pages={2149-55}
}
Probes isolated from DR and DQ beta cDNA and genomic clones were used in hybridizations to restriction enzyme-digested DNA from human homozygous typing cells (HTC) as well as other DR homozygous cells in order to estimate the number of beta genes in the DR/DQ class II region. Varying numbers of DR beta genes were found in HTC of different DR specificities, from possibly one in DR 8 cells to three in cells of DR 2 to 7. The DR beta genes of different specificities seem to be related to one… CONTINUE READING

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