HLA-DR antigens and the rubella-specific immune response in man.

Abstract

Several genetic markers, HLA-A, B and DR antigens, Gm and Km types, and ABO blood types, were studied on 78 rubella seronegative schoolgirls immunized with "TO336" rubella vaccine. A marked association was found between an HLA haplotype, HLA-Aw24-Bw52-DRHO, and the low antibody responsiveness to rubella virus. The association with the DR antigen was thought… (More)

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