HLA-DR and HLA-DQ alleles in patients from the south of Brazil: markers for leprosy susceptibility and resistance

@inproceedings{Silva2009HLADRAH,
  title={HLA-DR and HLA-DQ alleles in patients from the south of Brazil: markers for leprosy susceptibility and resistance},
  author={Samira A da Silva and Priscila Saamara Mazini and P{\^a}mela Guimar{\~a}es Reis and Ana Maria Sell and Luiza Tamie Tsuneto and Paulo Roberto Peixoto and Jeane EL Visentainer},
  booktitle={BMC infectious diseases},
  year={2009}
}
BACKGROUND Many epidemiological studies have shown that the genetic factors of the host play a role in the variability of clinical response to infection caused by M. leprae. With the purpose of identifying genes of susceptibility, the present study investigated the possible role of HLA-DRB1 and DQA1/DQB1 alleles in susceptibility to leprosy, and whether they account for the heterogeneity in immune responses observed following infection in a Southern Brazilian population. METHODS One hundred… CONTINUE READING
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Tipagem HLA-DQA e HLA-DQB por biologia molecular PCR-SSP, Média resolução

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