HLA-DR, DQ genotypes of celiac disease patients and healthy subjects from the West of Ireland.

@article{Michalski1996HLADRDG,
  title={HLA-DR, DQ genotypes of celiac disease patients and healthy subjects from the West of Ireland.},
  author={Joseph P. Michalski and Candace C. McCombs and Tomio Arai and Robert C. Elston and Tianxiu Cao and C F Mccarthy and Fiona M. Stevens},
  journal={Tissue antigens},
  year={1996},
  volume={47 2},
  pages={127-33}
}
Celiac disease (CD) has one of the strongest class II HLA associations of any human illness. We used DNA-RFLP typing to study the class II HLA genotypes of celiac disease patients from the West of Ireland, the geographic area with the highest rate of celiac disease in the world. We confirmed the high frequency of HLA-DR3 in this population, and we were also able to demonstrate the additional risk of developing celiac disease imparted by HLA-DR7. This was done by clearly distinguishing DR7,DQ2… CONTINUE READING

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