HLA-DQB1 Allele and Hypocretin in Korean Narcoleptics with Cataplexy

  title={HLA-DQB1 Allele and Hypocretin in Korean Narcoleptics with Cataplexy},
  author={Jong-Hyun Jeong and S Hong and Yoshihiro Kimura Shin and Jin Hee Han and Sung-Pil Lee},
  booktitle={Journal of Korean medical science},
Cataplexy is one of the most pathognomonic symptoms in narcolepsy. This study was designed to investigate the frequency of the HLA-DQB1 allele and cerebrospinal fluid (CSF) hypocretin levels in Korean narcoleptics with cataplexy as compared with those who do not have cataplexy. Seventy-two narcoleptics were selected based on polysomnography and multiple sleep latency test as well as their history and clinical symptoms at Sleep Disorders Clinic. The patients were divided into a narcolepsy with… CONTINUE READING

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