HLA-DPB1*0501-associated opticospinal multiple sclerosis: clinical, neuroimaging and immunogenetic studies.

@article{Yamasaki1999HLADPB10501associatedOM,
  title={HLA-DPB1*0501-associated opticospinal multiple sclerosis: clinical, neuroimaging and immunogenetic studies.},
  author={Kouhei Yamasaki and Ikuo Horiuchi and Motozumi Minohara and Yuji Kawano and Yasumasa Ohyagi and Takako Yamada and Futoshi Mihara and Hiroshi Ito and Yoshie Nishimura and Jyunichi Kira},
  journal={Brain : a journal of neurology},
  year={1999},
  volume={122 ( Pt 9)},
  pages={1689-96}
}
In order to clarify the relationship between the clinical phenotype and the human leucocyte antigen (HLA) in multiple sclerosis in Asians, 93 Japanese patients with clinically definite multiple sclerosis underwent clinical MRI and HLA-DPB1 gene typing studies. According to a neurological examination, 29 patients were classified as opticospinal multiple sclerosis, 17 as spinal multiple sclerosis and 47 as Western type multiple sclerosis showing the involvement of multiple sites in the CNS… CONTINUE READING

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