HLA-DP4 expression and immunity to NY-ESO-1: correlation and characterization of cytotoxic CD4+ CD25- CD8- T cell clones.

@article{Huarte2004HLADP4EA,
  title={HLA-DP4 expression and immunity to NY-ESO-1: correlation and characterization of cytotoxic CD4+ CD25- CD8- T cell clones.},
  author={Eduardo Huarte and Julia Karbach and Sacha Gnjatic and Armin Bender and Dirk Jaeger and Michael Arand and Djordje Atanackovic and Jonathan Skipper and Gerd Ritter and Yao-Tseng Chen and L. John Old and Alexander K. Knuth and E. P. Jaeger},
  journal={Cancer immunity},
  year={2004},
  volume={4},
  pages={15}
}
NY-ESO-1 is one of the most immunogenic cancer antigens known to date, eliciting spontaneous immune responses in approximately 50% of patients with NY-ESO-1+ cancers. Spontaneous CD4+ and CD8+ T cell responses were found in patients with detectable NY-ESO-1 serum antibody, indicating an integrated type of immune response induced by NY-ESO-1+ malignancies. A… CONTINUE READING