HLA-Cw*06 class I region rather than MICA is associated with psoriatic arthritis in Czech population

@article{Fojtkov2009HLACw06CI,
  title={HLA-Cw*06 class I region rather than MICA is associated with psoriatic arthritis in Czech population},
  author={Mark{\'e}ta Fojt{\'i}kov{\'a} and Jiř{\'i} {\vS}tolfa and Peter Novota and Pavl{\'i}na {\vC}ejkov{\'a} and Ctibor Dostal and M Cerna},
  journal={Rheumatology International},
  year={2009},
  volume={29},
  pages={1293-1299}
}
Psoriatic arthritis (PsA) is a chronic inflammatory joint disease which affects patients suffering from psoriasis. The genetic background especially the susceptibility loci on the short arm of the chromosome six contribute to PsA development. In our study, we looked for the role of the MICA and HLA-Cw genes polymorphisms in PsA pathogenesis. We investigated 100 PsA patients and 94 healthy Czech individuals. We found an association between HLA-Cw*06 and PsA namely PsA with psoriasis type I (age… CONTINUE READING
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