HLA-B27 in the Greek Cypriot population: distribution of subtypes in patients with ankylosing spondylitis and other HLA-B27-related diseases. The possible protective role of B*2707.

@article{VarnavidouNicolaidou2004HLAB27IT,
  title={HLA-B27 in the Greek Cypriot population: distribution of subtypes in patients with ankylosing spondylitis and other HLA-B27-related diseases. The possible protective role of B*2707.},
  author={Agathi Varnavidou-Nicolaidou and Katerina Karpasitou and Dora Georgiou and Galatia Stylianou and Avgousta Kokkofitou and Christodoulides Michalis and Constantinou Constantina and Christiana Gregoriadou and George Kyriakides},
  journal={Human immunology},
  year={2004},
  volume={65 12},
  pages={1451-4}
}
The major purpose of the present study was to investigate the frequency of human leukocyte antigen (HLA)-B27 alleles in healthy controls and in patients with ankylosing spondylitis (AS) and other HLA-B27-related diseases in the Greek Cypriot population. We selected 102 HLA-B27-positive individuals (60 controls and 42 patients). Typing of the HLA-B27 alleles was performed by polymerase chain reaction amplification with sequence-specific primers. Only two alleles were detected in the patient… CONTINUE READING

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