HLA-B27-associated reactive arthritis: pathogenetic and clinical considerations.

  title={HLA-B27-associated reactive arthritis: pathogenetic and clinical considerations.},
  author={In{\'e}s Colmegna and Raquel S Cuchacovich and Luis Rolan Espinoza},
  journal={Clinical microbiology reviews},
  volume={17 2},
Current evidence supports the concept that reactive arthritis (ReA) is an immune-mediated synovitis resulting from slow bacterial infections and showing intra-articular persistence of viable, non-culturable bacteria and/or immunogenetic bacterial antigens synthesized by metabolically active bacteria residing in the joint and/or elsewhere in the body. The mechanisms that lead to the development of ReA are complex and basically involve an interaction between an arthritogenic agent and a… CONTINUE READING

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