HLA-B27: an important genetic risk factor for lone aortic regurgitation and severe conduction system abnormalities.


PURPOSE HLA-B27, an immunogenetic marker that is present in 8 percent of the white population around the world, has been found to be an important risk factor for the development of a group of rheumatic disorders, the seronegative spondyloarthropathies. Our objective was to assess the possible role of HLA-B27 and the associated inflammatory disease process… (More)


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