HLA: linkage with rheumatoid arthritis or seropositivity.

  title={HLA: linkage with rheumatoid arthritis or seropositivity.},
  author={Alan Jonathan Silman and Bill Ollier and M F McDermott},
  journal={The Journal of rheumatology},
  volume={15 8},
HLA haplotype sharing was compared in sibships from multicase families with rheumatoid arthritis (RA), subdivided by rheumatoid factor status, to investigate the claim that HLA is linked more to RA severity than susceptibility. Considerable deviation from expected (Mendelian) inheritance towards greater sharing of inherited parental haplotypes was observed… CONTINUE READING