HL 752: a potent and long-acting antispasmodic agent.

@article{BalTembe1997HL7A,
  title={HL 752: a potent and long-acting antispasmodic agent.},
  author={Swati Bal-Tembe and Dilip Bhedi and Arun Kumar Mishra and Ramanujam Rajagopalan and Anil Vasantrao Ghate and P. Subbarayan and Narayan S. Punekar and Ashish V. Kulkarni},
  journal={Bioorganic \& medicinal chemistry},
  year={1997},
  volume={5 7},
  pages={
          1381-7
        }
}
4 Citations

Procede de synthese de promedicaments a partir de derives de 1-acyl-alkyl et compositions correspondantes

L'invention porte sur un procede de synthese de derives de 1-(acyloxy)-alkyl a partir de derives de 1-acyl-alkyl. Ce procede, qui est generalement mis en oeuvre de maniere specifique, avec des

Сучасні підходи до усунення вісцерального болю

New opportunities for effective treatment of visceral pain are opened by the drug Neospastil® (PJSC «Pharmaceutical Company «Darnitsa»), which combines the benefits of nonsteroidal anti-inflammatory drugs (ketorolac tromethamine) with antispasmodic effect of cholinolytics, ganglioblockers and pheny toin phenytoin.

Сучасні підходи до усунення вісцерального болю

New opportunities for effective treatment of visceral pain are opened by the drug Neospastil® (PJSC «Pharmaceutical Company «Darnitsa»), which combines the benefits of nonsteroidal anti-inflammatory drugs (ketorolac tromethamine) with antispasmodic effect of cholinolytics, ganglioblockers and pheny toin phenytoin.

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The kinetics of substrate hydrolysis by pig liver esterase show activation by various substrates as well as activation by organic solvents (both Vmax and Km increase) and indicates that an aromatic or a hydrophobic structure and a carbonyl group are required for optimal interaction with the effector site.