HIV type 1 tropism and inhibitors of viral entry: clinical implications.

@article{Weber2006HIVT1,
  title={HIV type 1 tropism and inhibitors of viral entry: clinical implications.},
  author={Jan Weber and Helen Piontkivska and Miguel E Qui{\~n}ones-Mateu},
  journal={AIDS reviews},
  year={2006},
  volume={8 2},
  pages={60-77}
}
Since their discovery in 1996, the two main coreceptors used by human immunodeficiency virus type 1 (HIV-1) to enter human cells (CCR5 and CXCR4) have been the subject of numerous scientific articles. A recent search in PubMed (www.pubmed.gov) using "HIV coreceptor" as keywords led to more than 1100 original research publications and 90 review articles. This number skyrocketed to more than double if we used "HIV CCR5". Most of the reviews described in detail several aspects of HIV tropism… CONTINUE READING