HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy.

@article{Pillay2008HIVT1,
  title={HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy.},
  author={Visva Pillay and Candice Pillay and R. Kantor and François Venter and Leon Levin and Lynn Morris},
  journal={AIDS research and human retroviruses},
  year={2008},
  volume={24 11},
  pages={1449-54}
}
The emergence of HIV drug resistance is a major obstacle to effective antiretroviral (ARV) treatments. This study examined the drug resistance profiles among South African patients virologically failing ARV therapies between 2000 and 2003, prior to the introduction of a national treatment program. Samples were obtained from 65 HIV-1 subtype C-infected patients (39 children and 26 adults) who had received at least two nucleoside reverse transcriptase inhibitors (NRTIs) and either a nonnucleoside… CONTINUE READING
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