HIV-therapy associated lipodystrophy: experimental and clinical evidence for the pathogenesis and treatment.

@article{Stankov2007HIVtherapyAL,
  title={HIV-therapy associated lipodystrophy: experimental and clinical evidence for the pathogenesis and treatment.},
  author={Metodi V. Stankov and Georg M N Behrens},
  journal={Endocrine, metabolic & immune disorders drug targets},
  year={2007},
  volume={7 4},
  pages={237-49}
}
The introduction of highly active antiretroviral therapy (HAART) including nucleoside reverse transcriptase inhibitors (NRTI) and protease inhibitors (PI) has dramatically improved the morbidity and mortality in HIV-infected patients. Unfortunately, HAART has been associated with several side effects among which the development of lipodystrophy syndrome remains a major clinical issue. It is characterized by fat redistribution dominated by peripheral fat loss and complex metabolic alterations… CONTINUE READING
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