HIV protease inhibitors: a review of molecular selectivity and toxicity

@inproceedings{Lv2015HIVPI,
  title={HIV protease inhibitors: a review of molecular selectivity and toxicity},
  author={Zhengtong Lv and Yuan Chu and Yong Wang},
  booktitle={HIV/AIDS},
  year={2015}
}
Highly active antiretroviral therapy (HAART) is recognized as the most effective treatment method for AIDS, and protease inhibitors play a very important role in HAART. However, poor bioavailability and unbearable toxicity are their common disadvantages. Thus, the development of safer and potentially promising protease inhibitors is eagerly needed. In this review, we introduced the chemical characteristics and associated side effects of HIV protease inhibitors, as well as the possible off… CONTINUE READING
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