HIV interaction with endosomes in macrophages and dendritic cells.

@article{Kramer2005HIVIW,
  title={HIV interaction with endosomes in macrophages and dendritic cells.},
  author={Beatrice Kramer and Annegret Pelchen-Matthews and Magdalena Deneka and Eduardo Carvalho Garcia and Vincent Piguet and Mark Marsh},
  journal={Blood cells, molecules & diseases},
  year={2005},
  volume={35 2},
  pages={136-42}
}
The human immunodeficiency virus type 1 (HIV-1) is an enveloped retrovirus that undergoes assembly at specific sites in infected cells. In macrophages, at least, this assembly occurs primarily on a subset of endocytic organelles that contain some of the markers found in late endosomes or multivesicular bodies (MVBs), in particular CD63. The budding of virus particles into endosomes has many features in common with the formation of exosomes and some limited biochemical comparison of HIV-1… CONTINUE READING