HIV infection-related premature immunosenescence: high rates of immune exhaustion after short time of infection.

@article{FerrandoMartnez2011HIVIP,
  title={HIV infection-related premature immunosenescence: high rates of immune exhaustion after short time of infection.},
  author={Sara Ferrando-Mart{\'i}nez and Ezequiel Ruiz-mateos and Mar{\'i}a Concepci{\'o}n Romero-S{\'a}nchez and Ma {\'A}ngeles Mu{\~n}oz-Fern{\'a}ndez and Pompeyo Viciana and Miguel Genebat and Manuel Leal},
  journal={Current HIV research},
  year={2011},
  volume={9 5},
  pages={289-94}
}
Premature immunosenescence has been reported in different HIV scenarios. However, how premature is the HIV-related immunosenescent phenotype is still unknown. Thus, the aim of this study was to analyze the immunosenescent status of young viraemic naive HIV-infected individuals, with less than four years from infection. To this end, replicative senescence, activation and proliferation T-cell levels were analyzed in chronically HIV-infected young individuals and both, elderly and young healthy… CONTINUE READING