HIV infection and hepatic enzyme abnormalities: intricacies of the pathogenic mechanisms.

@article{Pol2004HIVIA,
  title={HIV infection and hepatic enzyme abnormalities: intricacies of the pathogenic mechanisms.},
  author={Stanislas Pol and Pascal Lebray and Anais Vallet-Pichard},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2004},
  volume={38 Suppl 2},
  pages={S65-72}
}
Liver enzyme elevations are common in human immunodeficiency virus (HIV)-infected patients, and their diagnosis or management may be difficult because of the intricacies of the pathogenic mechanisms involved. These include hepatotoxicity related to the highly active antiretroviral therapy (HAART) regimen, idiosyncratic or immunoallergic mechanisms, and direct cytotoxicity enhanced by an underlying liver disease. Liver enzyme abnormalities may also reflect hepatitis B (HBV) or hepatitis C (HCV… CONTINUE READING
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