HIV associated thrombotic microangiopathy.

  title={HIV associated thrombotic microangiopathy.},
  author={Shadab Ahmed and Rina K Siddiqui and Anita Karim Siddiqui and Syed Ali Hyder Zaidi and Joseph Steven Cervia},
  journal={Postgraduate medical journal},
  volume={78 923},
Thrombotic microangiopathy (TMA) is a known complication of HIV infection. Endothelial cell injury appears to be the primary event causing platelet activation and deposition in the microvasculature. Direct cytopathic roles of HIV as well as other factors such as malignancy, drugs, and infectious agents have been implicated in the pathogenesis of HIV-TMA. Although the the majority of patients present in a more advanced stage of HIV disease, TMA can be the initial presenting symptom of HIV… CONTINUE READING


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