HIV-associated neuropathies: role of HIV-1, CMV, and other viruses.

@article{Kolson2001HIVassociatedNR,
  title={HIV-associated neuropathies: role of HIV-1, CMV, and other viruses.},
  author={Dennis L Kolson and Francisco Gonz{\'a}lez-Scarano},
  journal={Journal of the peripheral nervous system : JPNS},
  year={2001},
  volume={6 1},
  pages={
          2-7
        }
}
The role of the human immunodeficiency virus (HIV) and other viruses in the development of neuropathies associated with HIV infection is controversial. Distal symmetric polyneuropathy (DSP), the most common subtype of HIV-associated neuropathy, is characterized by an abundance of reactive macrophages within the peripheral nerve, but HIV replication is limited to a small percentage of the macrophages. Thus, the pathological destruction may be mediated by pro-inflammatory signals amplified by… CONTINUE READING
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