HIV antigen in the brains of patients with the AIDS dementia complex.

@article{PumarolaSu1987HIVAI,
  title={HIV antigen in the brains of patients with the AIDS dementia complex.},
  author={Tom{\`a}s Pumarola-Su{\~n}{\'e} and Bradford Navia and Carlos Cordon-Cardo and Eun Song Cho and Richard W. Price},
  journal={Annals of neurology},
  year={1987},
  volume={21 5},
  pages={490-6}
}
Human immunodeficiency virus infection was identified immunohistochemically in the brains of 8 patients with acquired immune deficiency syndrome dementia complex. Using a monoclonal antibody against a structural viral protein (p25), infection was detected in white matter and basal ganglia in a distribution paralleling that of the major neuropathological abnormalities. Viral antigen was identified principally in perivascular and parenchymal macrophages and in multinucleated cells of macrophage… CONTINUE READING