HIV antigen and DNA in AIDS spinal cords correlate with macrophage infiltration but not with vacuolar myelopathy.

@article{Petito1994HIVAA,
  title={HIV antigen and DNA in AIDS spinal cords correlate with macrophage infiltration but not with vacuolar myelopathy.},
  author={Carol K. Petito and Darleen Vecchio and Yu T Chen},
  journal={Journal of neuropathology and experimental neurology},
  year={1994},
  volume={53 1},
  pages={86-94}
}
Since the relationship between vacuolar myelopathy (VM) and HIV infection of the spinal cord is unclear, we studied 74 cases of VM in AIDS patients for associated spinal cord and brain diseases, the presence of HIV antigens (n = 54) and amplified DNA (n = 7) and serum levels of vitamin B12 and folic acid (n = 6). Necrosis of the medial F. gracilis was present in 14%, HIV myelitis in 9%, cytomegalovirus myelitis in 3% and microglial nodules in 16%. HIV-immunoreactive macrophages were encountered… CONTINUE READING

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