HIV accessory proteins and surviving the host cell

  title={HIV accessory proteins and surviving the host cell},
  author={J. Anderson and T. Hope},
  journal={Current HIV/AIDS Reports},
  • J. Anderson, T. Hope
  • Published 2004
  • Medicine, Biology
  • Current HIV/AIDS Reports
  • Human immunodeficiency virus generates the accessory proteins Nef, viral infectivity factor (Vif), viral protein R, and viral protein U or viral protein X during viral replication in host cells. Although the significance of these accessory proteins is often lost in vitro, they are essential for viral pathogenesis in vivo. Therefore, these proteins have much potential as antiviral targets. Recent data reveal Vif perturbs an ill-defined antiviral pathway in host cells allowing HIV replication… CONTINUE READING
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