HIV Treatment as Prevention: Considerations in the Design, Conduct, and Analysis of Cluster Randomized Controlled Trials of Combination HIV Prevention

@inproceedings{Boily2012HIVTA,
  title={HIV Treatment as Prevention: Considerations in the Design, Conduct, and Analysis of Cluster Randomized Controlled Trials of Combination HIV Prevention},
  author={Marie-Claude Boily and Beno{\^i}t Mass{\'e} and Ramzi A Alsallaq and Nancy S. Padian and Jeffrey W Eaton and Juan F Vesga and Timothy B Hallett},
  booktitle={PLoS medicine},
  year={2012}
}
The rigorous evaluation of the impact of combination HIV prevention packages at the population level will be critical for the future of HIV prevention. In this review, we discuss important considerations for the design and interpretation of cluster randomized controlled trials (C-RCTs) of combination prevention interventions. We focus on three large C-RCTs that will start soon and are designed to test the hypothesis that combination prevention packages, including expanded access to… CONTINUE READING
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