HIV Infection of T Cells: Actin-in and Actin-out

@article{Liu2009HIVIO,
  title={HIV Infection of T Cells: Actin-in and Actin-out},
  author={Yin Liu and N. Belkina and S. Shaw},
  journal={Science Signaling},
  year={2009},
  volume={2},
  pages={pe23 - pe23}
}
The coordinated activities of various actin-binding proteins facilitate entry of HIV into T cells. Three studies shed light on the decade-old observation that the actin cytoskeleton is hijacked to facilitate entry of HIV into its target cells. Polymerization of actin is required to assemble high concentrations of CD4 and CXCR4 at the plasma membrane, which promote viral binding and entry in both the simple model of infection by free virus and the more physiologically relevant route of infection… Expand
The trinity of the cortical actin in the initiation of HIV-1 infection
Gelsolin activity controls efficient early HIV-1 infection
Plasma membrane signaling in HIV-1 infection.
All-Round Manipulation of the Actin Cytoskeleton by HIV
HIV-1 Balances the Fitness Costs and Benefits of Disrupting the Host Cell Actin Cytoskeleton Early after Mucosal Transmission.
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